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KMID : 0363320200410030531
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Journal of Korean Oriental Internal Medicine
2020 Volume.41 No. 3 p.531 ~ p.541
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A Study on the Change of Liver Function Level in Patients Admitted to Korean Medicine Hospital: A Case of One Drug-induced Liver Injury Patient
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Kim Geun-Yeob
Jung Nu-Ri
Choi Yu-Jin
Shin Seon-Mi
Kim Ki-Tae
Ko Heung
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Abstract
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From January 2014 to December 2016, 38 out of 153 inpatients admitted to the Korean Medicine Hospital for more than one month underwent follow-up blood tests to evaluate their liver function levels, and one drug-induced liver injury (DILI) patient was observed.
1. At the time of admission, six (15.8%) of the 38 patients had abnormal alanine aminotransferase (ALT) levels and five of them recovered after hospitalization.
2. At follow-up, two (5.3%) patients had a Council for International Organizations of Medical Science (CIOMS)-based liver injury. One was identified as a liver injury accompanied by pneumonia, and one was judged as a liver injury caused by the drug.
3. The patient had a suspected DILI and completely recovered after 13 days while discontinuing the herbal medication and by using Sanggangunbi-tang (生肝健脾湯).
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KEYWORD
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drug-induced liver injury (DILI), herb, alanine aminotransferase (ALT), CIOMS, traditional Korean medicine (TKM)
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